Fig. 8From: Estimation of relative biological effectiveness of 225Ac compared to 177Lu during [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy using TOPAS/TOPAS-nBio/MEDRASExemplary dose–effect curves of 177Lu and 225Ac for cell geometry 1 and full internalization. Initial DSBs are shown as full circles, post-repair DSBs are depicted as circles with white background color. Error bars of number of DSBs after repair are shown in blackBack to article page