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Table 1 Patient characteristics

From: Predicting [177Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [68Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling

Characteristic

Median (range) or number (%)

Sex

 

 Male (n)

4 (44%)

 Female (n)

5 (56%)

Age (years)

70 (44–76)

Weight (kg)

75.0 (55.0–108)

Height (cm)

174 (160–189)

Creatinine clearance (mL/min)

68.8 (53.6–111)

Tumor volume of target tumors (representing the tumor compartment)a (mL)

80.0 (7.81–212)

Total tumor volumeb (mL)

283 (22.4–644)

Injected radioactivity

 [68Ga]Ga-HA-DOTATATE (MBq)

96.0 (75.6–102)

 [177Lu]Lu-HA-DOTATATE (MBq)

7271 (7176–7613)

Injected peptide amount

 [68Ga]Ga-HA-DOTATATE (µg)

5.23 (3.01–9.64)

 [177Lu]Lu-HA-DOTATATE (µg)

151 (132–178)

  1. aTarget tumors represent lesions with a diameter > 2 cm and a maximum of five segmented lesions of which two per organ system per patient
  2. bSum of tumor volumes of all tumors (including target tumors)