Table 2 ODs and ED for (+)-[18F]flubatine based on piglet data
Target organ | OD | SD | ED contribution | SD |
|---|---|---|---|---|
(mSv/MBq) | (mSv/MBq) | |||
Adrenals | 1.11E−02 | 7.64E−04 | 9.57E−05 | 6.57E−06 |
Brain | 3.23E−02 | 3.24E−03 | 3.23E−04 | 3.24E−05 |
Breasts | 6.21E−03 | 5.15E−04 | 7.45E−04 | 6.18E−05 |
Gallbladder wall | 1.81E−02 | 1.18E−03 | 1.56E−04 | 1.02E−05 |
LLI wall | 1.15E−02 | 4.04E−04 | 6.88E−04 | 2.42E−05 |
Small intestine | 1.48E−02 | 1.00E−03 | 1.27E−04 | 8.61E−06 |
Stomach wall | 1.10E−02 | 6.51E−04 | 1.32E−03 | 7.81E−05 |
ULI wall | 1.52E−02 | 1.15E−03 | 9.12E−04 | 6.92E−05 |
Heart wall | 1.42E−02 | 2.15E−03 | 1.22E−04 | 1.85E−05 |
Kidneys | 4.51E−02 | 6.50E−03 | 3.88E−04 | 5.59E−05 |
Liver | 2.69E−02 | 4.78E−03 | 1.07E−03 | 1.91E−04 |
Lungs | 1.39E02 | 2.00E−04 | 1.67E−03 | 2.40E−05 |
Muscle | 7.77E−03 | 4.03E−04 | 6.68E−05 | 3.46E−06 |
Ovaries | 1.07E−02 | 2.08E−04 | 8.53E−04 | 1.67E−05 |
Pancreas | 2.24E−02 | 1.78E−03 | 1.93E−04 | 1.53E−05 |
Red marrow | 1.15E−02 | 1.07E−03 | 1.38E−03 | 1.28E−04 |
Osteogenic cells | 1.35E−02 | 1.21E−03 | 1.35E−04 | 1.21E−05 |
Skin | 5.87E−03 | 4.13E−04 | 5.87E−05 | 4.13E−06 |
Spleen | 2.01E−02 | 9.07E−04 | 1.73E−04 | 7.80E−06 |
Testes | 7.70E−03 | 6.51E−05 | – | – |
Thymus | 1.82E−02 | 3.27E−03 | 1.56E−04 | 2.81E−05 |
Thyroid | 1.77E−02 | 8.90E−03 | 7.07E−04 | 3.56E−04 |
Urinary bladder wall | 7.17E−02 | 2.63E−02 | 2.87E−03 | 1.05E−03 |
Uterus | 1.28E−02 | 1.01E−03 | 1.10E−04 | 8.73E−06 |
Total body | 9.39E−03 | 7.64E−04 | – | – |
ED (mSv/MBq) | 1.43E−02 | 2.60E−04 | ||
ED (mSv/MBq) ICRP 60 | 1.52E−02 | 5.0E−04 | ||